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Amlodipine Besylate is a class of calcium channel blockers. It is used to treat hypertension (high blood pressure). Amlodipine acts on blood vessels and expands the blood vessels more than usual and decreases blood pressure (as we know area is inversely proportional to pressure). Lowering hypertension also reduces the risk of cardiovascular events, strokes and some other problems. One of the Amlodipine product on the market is Norvasc.

Amlodipine Besylate API

CAS Number: 111470-99-6

Molecular Weight: 567.05

Melting point: 199-201°C

Storage Temperature: Store at RT

Mechanism of action:

Amlodipine Besylate prohibits the transmembrane influx of calcium ions into the vascular smooth and cardiac muscle.

Amlodipine Besylate is a dihydropyridine calcium antagonist that attaches to both dihydropyridine and non-dihydropyridine binding sites. The contractile manners of cardiac muscle and vascular smooth muscle are dependent on the movement of extracellular calcium ions into these cells through specific ion channels.

Amlodipine Besylate prohibits calcium ion influx across cell membranes selectively, with a superior effect on vascular smooth muscle cells than on cardiac muscle cells.  It is more selective for vascular smooth muscle than for the cardiac muscle. 

About Sidhiv Pharma:

Sidhiv Pharma is an international pharmaceutical and chemical export company based in India. We have been in business with 4 decades of industry experience and now support International businesses, manufacturers and export pharma API, a wide variety of chemicals, and herbal extracts at a very affordable cost.

Sidhiv Pharma is a full-service export company based in India. We developed this platform to help international buyers get export quality material from India without worrying about the supplier size, quality, or quantity.

Our mission is to deliver quality materials and fulfill a business need in the best and affordable way possible. We value long term relationships and support businesses create a reliable export chain from India. Our supplier’s manufacture drugs that are approved by FDA and follow GMP, WHOGMP standards. Sidhiv Pharma focus is to keep clients and suppliers safe and we do it by creating a system that satisfies both parties. 

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